Since 1949, Wile E. Coyote has been chasing and trying to catch the Road Runner, but is never successful. Instead of his animal instincts, the Coyote uses absurdly complex Acme contraptions to try to catch his prey, which comically backfire, with the Coyote often getting injured in slapstick fashion. When Wile E. Coyote does finally get the Road Runner on his dinner plate, he'll know that persistence is the key to success!